Selection of references from the laboratory: LAMBDA peristaltic pumps
The best references are the successful applications of users of LAMBDA peristaltic pumps. We are always looking forward to reading interesting news from your laboratory and about your application of peristaltic pumps in research & industry!
LAMBDA MULTIFLOW peristaltic pumps a sheath flow for driving the sample flow into a central core, allowing the particles to pass the uniformly illuminated area of the DFLS system.
Xiao, D., Zang, Z., Sapermsap, N., Wang, Q., Xie, W., Chen, Y. & Li, D.D.U. (2021). Dynamic fluorescence lifetime sensing with CMOS single-photon avalanche diode arrays and deep learning processors. Biomed. Opt. Express 12, 3450-3462 (2021);
Keywords: DFLS; Dynamic Fluorescence Lifetime Sensing; TCSPC; Time-Correlated Single-Photon Counting; Fast-Moving Particles; Biomedical Science; Fluorescence Lifetimes; Flow Chamber
References of peristaltic pumps in Biotechnology
Here, you will find the relevant references in the field of Biotechnology as acid pump, base pump, feed pump and harvest pump which are mentioned in the scientific publications:
Production of recombinant cytochrome in a bioreactor: the feed was pumped through a PRECIFLOW peristaltic pump controlled by the process information management system and its addition was monitored gravimetrically.
Hausjell, J., Schendl, D., Weissensteiner, J., Molitor, C., Halbwirth, H. & Spadiut, O. (2020). Recombinant production of a hard-to-express membrane-bound cytochrome P450 in different yeasts—Comparison of physiology and productivity. Yeast. 2020; 37: 217– 226;
Keywords: Chalcone 3-hydroxylase, Pichia pastoris, Saccharomyces cerevisiae, Yeast, Physiology, Recombinant Protein Production
LAMBDA Peristaltic Pumps were used with third-party bioreactors for precise pumping of liquids
Hofer, A., Kroll, P. & Herwig, C. (2019). Automated sampling and on-line analytics to increase process understanding. Securecell AG, In der Luberzen 29, CH-8902 Urdorf, Switzerland and TU Wien, Gumpendorfer Strasse 1a, A-1060 Wien, Austria.
Keywords: Bioprocesses; Automation technology; Liquid handling; Facilitating; Automated sampling; On-line analytics; Process monitoring and control; Sample processing system; Real-time monitoring; Mammalian cell culture process; Biotechnology
LAMBDA PRECIFLOW peristaltic pump used as feed pump for glycerol during fermentation of E. coli and for producing chitin beads
Lavallaz, G. & Crelier, S. (2010). Purification de GFP avec et sans marqueur d'affinité. Diploma thesis, HES-SO Valais, Sion.
https://doc.rero.ch/record/22518 (03. June 2021)
Keywords: fluorescent proteins; separation and purification of proteins and peptides
Chemostat, Turbidostat or Perfusion: References for feed pumps and harvest pumps
LAMBDA peristaltic pumps as reliable feed- and harvest-pumps during 140 days of continuous fermentation
Brodowski, F., Lezyk, M., Gutowska & Oleskowicz-Popiel, P. (2022). Effect of external acetate on lactate-based carboxylate platform: Shifted lactate overloading limit and hydrogen co-production. Science of The Total Environment, Volume 802, 2022, 149885, ISSN 0048-9697.
Keywords: Chain elongation, Carboxylate platform, Caproate, Hydrogen, Lactate overloading, Acetate
Feed, loop, bleed and harvest: LAMBDA PRECIFLOW peristaltic pumps for continuous cultivation of extreme halophiles in customized pilot scale bioreactor
Mahler, N., Tschirren, S., Pflügl, S. & Herwig, CH. (2018). Optimized bioreactor setup for scale-up studies of extreme halophilic cultures. Biochemical Engineering Journal, Volume 130, 2018, Pages 39-46, ISSN 1369-703X.
Keywords: Continuous bioprocessing; Bubble column; Cell retention; Halophiles; Salt recycling; Haloferax mediterranei; Saline conditions; Bubble column reactor; Stirred tank creactor; Oxygen tranfer rate; Mass transfer; Continuous haliophilic processes.
Turbidostat composed of two PRECIFLOW peristaltic pumps with RS-232 interface for automated protein production in Escherichia coli cultures
Milias-Argeitis, A., Rullan, M., Aoki, S. et al. (2016). Automated optogenetic feedback control for precise and robust regulation of gene expression and cell growth. Nat Commun 7, 12546.
Keywords: Expression system; Industrial microbiology; Optogenetics; superfolder green fluorescent protein (sfGFP);
Inflow of M. marburgensis chemostat culture DoE screening was controlled gravimetrically by designated PRECIFLOW pump set-point
Bernacchi, S., Rittmann, S., Seifert, A. H., Krajete, A. & Herwig, C. (2014). Experimental methods for screening parameters influencing the growth to product yield (Y(x/CH4)) of a biological methane production (BMP) process performed with Methanothermobacter marburgensis. AIMS Bioengineering, 2014, 1(2): 72-87.
Keywords: Design of Experiments; chemostat; dynamic experiments; bioprocess quantification; carbon balance, biological methanogenesis, bioCH4
Feed flow rate was kept constant by controlling the speed of the PRECIFLOW peristaltic pump in continuous culture of Methanothermobacter marburgensis
Seifert, A.H., Rittmann, S. & Herwig, C. (2014). Analysis of process related factors to increase volumetric productivity and quality of biomethane with Methanothermobacter marburgensis. Applied Energy, Volume 132, 2014, Pages 155-162, ISSN 0306-2619.
Keywords: Archaea; Biological methanogenesis; Continuous culture; Gas/liquid mass transfer; CO2; H2; CH4; Quantification
Digital PRECIFLOW as feed pump, bleed pump and cell-free harvest pump to maximize the productivity of extreme halophilic archaeon in a bioreactor equipped with an external cell retention system
Lorantfy, B., Ruschitzka, P. & Herwig, C. (2014). Investigation of physiological limits and conditions for robust bioprocessing of an extreme halophilic archaeon using external cell retention system. Biochemical Engineering Journal, Volume 90, 2014, Pages 140-148, ISSN 1369-703X.
Keywords: Halophilic Archaea; Microfiltration for cell retention; Integrated processing; Bioprocess design; Bioprocess monitoring; Ultrafiltration
Feed pump: In a continuous mode of culture, medium was fed by PRECIFLOW peristaltic pump operated on controlled set-points for designated dilution rates (D)
Martinez-Porqueras, E., Rittmann, S. & Herwig, C. (2013). Analysis of H2 to CO2 yield and physiological key parameters of Enterobacter aerogenes and Caldicellulosiruptor saccharolyticus. International Journal of Hydrogen Energy, Volume 38, Issue 25, 2013, Pages 10245-10251, ISSN 0360-3199.
Keywords: Glucose; Xylose; Hydrogen productivity; Hydrogen to carbon dioxide yield; Hydrogen to substrate yield
Feed flow rate kept constant by controlling PRECIFLOW pump speed to achieve a medium dilution rae (D) of 0.05 per hour (h-1) in anaerobic bioreactor
Seifert, A.H., Rittmann, S., Bernacchi, S. & Herwig, C. (2013). Method for assessing the impact of emission gasses on physiology and productivity in biological methanogenesis. Bioresource Technology, Volume 136, 2013, Pages 747-751, ISSN 0960-8524.
Keywords: Biomethane production; Industrial and biogenic waste gas; Biological methanogenesis; Bioreactor; Thermophilic culture
Continuous controlled inflow of nutrient medium fed to the bioreactor by PRECIFLOW peristaltic pump to obtain the desired dilution rate (D)
Martinez-Porqueras, E., Wechselberger, P. & Herwig, C. (2013). Effect of medium composition on biohydrogen production by the extreme thermophilic bacterium Caldicellulosiruptor saccharolyticus. International Journal of Hydrogen Energy, Volume 38, Issue 27, 2013, Pages 11756-11764, ISSN 0360-3199.
Keywords: Caldicellulosiruptor saccharolyticus; Defined medium; Complex medium; Xylose; Double nutrient limitation; Hydrogen productivity
Feed pump PRECIFLOW for designated medium dilution rates of Methanothermobacter marburgensis grown in continuous cultures
Rittmann, S., Seifert, A. & Herwig, C. (2012). Quantitative analysis of media dilution rate effects on Methanothermobacter marburgensis grown in continuous culture on H2 and CO2. Biomass and Bioenergy, Volume 36, 2012, Pages 293-301, ISSN 0961-9534.
Keywords: Methanogenesis; Methanothermobacter marburgensis; Dynamic experiment; Continuous culture; Liquid dilution rate
LAMBDA PRECIFLOW feed & harvest pumps for animal cell perfusion culture with spin-filter
Vallez-Chetreanu, F., Fraisse Ferreira, L.G., Rabe, R., von Stockar, U. & Marison, I.W. (2007). An on-line method for the reduction of fouling of spin-filters for animal cell perfusion cultures. Journal of Biotechnology, Volume 130, Issue 3, 2007, Pages 265-273, ISSN 0168-1656.
Keywords: Animal cell; Perfusion culture; Spin-filter; Fouling; Vibration; Piezo-electric
LAMBDA PRECIFLOW feed & harvest pumps in perfusion with spin-filter to study the animal cell retention
Vallez-Chetreanu, F. (2006). Characterization of the mechanism of action of spin-filters for animal cell perfusion cultures. PhD diss. NO 3488, École Polytechnique Fédérale de Lausanne, Switzerland.
https://infoscience.epfl.ch/record/78660/files/EPFL_TH3488.pdf (1. Juni 2021)
Keywords: Perfusion culture; CHO animal cell; Separation; Spin–filter; Retention; Fouling; Response surface methodology; Filter vibration; Piezoelectric.
Feed pump PRECIFLOW in fed-batch and continuous cultures of yeast Saccharomyces cerevisiae to maintain a constant dilution rate (D)
Stark, D., Zala, D., Münch, T., Sonnleitner, B., Marison, I.W. & von Stockar, U. (2003). Inhibition aspects of the bioconversion of l-phenylalanine to 2-phenylethanol by Saccharomyces cerevisiae. Enzyme and Microbial Technology, Volume 32, Issue 2, 2003, Pages 212-223, ISSN 0141-0229.
Keywords: 2-Phenylethanol; l-Phenylalanine; Saccharomyces cerevisiae; Inhibition kinetics; Metabolic uncoupling
pH was maintained at 3.5 (±0.01) by PRECIFLOW peristaltic pump in whey chemostat culture
Castrillo, J.I. & Ugalde, U.O. (1993). Patterns of energy metabolism and growth kinetics of Kluyveromyces marxianus in whey chemostat culture. Appl Microbiol Biotechnol 40, 386–393 (1993).
Keywords: Biomass; Whey; Chemostat culture, Kluyveromyces marxianus, Aerobic
Fed-batch: References for the LAMBDA feed pumps
LAMBDA PRECIFLOW peristaltic pump fits the requirements for substrate feeding in shaking flasks. The pump can convey flow rates between 0.01 and 60 mL h-1.
Wagner, S.G., Mähler, C., Polte, I., von Poschinger, J., Löwe, H., Kremling, A, et al. (2019). An automated and parallelised DIY-dosing unit for individual and complex feeding profiles. Construction, validation and applications. PLoS ONE 14(6): e0217268.
Keywords: Industrial applications; Scalable and controllable laboratory procedures; Biotechnological research; Process; Growth rates; Production; feeding strategy; Bioprocess development; Up-scaling; Feeding profiles; Shaking flasks; E. coli HMS174/DE3; pTRA-51hd plasmid; Substrate; Microencapsulation; Pseudomonas putida; his-tagged eGFP; IMAC.
Adaptive feeding strategy with real time signal (Lucullus) controlled feed rate of the PRECIFLOW pump in fed-batch process
Konakovsky, V., Clemens, C., Müller, M.M., Bechmann, J., Berger, M., Schlatter, S. & Herwig, C. (2016). Metabolic Control in Mammalian Fed-Batch Cell Cultures for Reduced Lactic Acid Accumulation and Improved Process Robustness. Bioengineering 2016, 3, 5.
Keywords: CHO cell culture; scale-down; fed batch; automation; Lactic acid control; pH; metabolic control; MVDA; uncertainty; online analyser
PRECIFLOW feed pump for the production of 2-phenylethanol (PEA) by in situ product removal (ISPR) method
Stark, D., Kornmann, H., Munch, T., Sonnleitner, B., Marison, I. W. & von Stockar, U. (2003). Novel Type of In Situ Extraction: Use of Solvent Containing Microcapsules for the Bioconversion of 2-Phenylethanol from L-Phenylalanine by Saccharomyces cerevisiae. Biotechnol Bioeng. 2003 Aug 20; 83(4):376-85.
Keywords: In-situ product recovery; Microencapsulation of solvent; 2-phenylethanol; Extractive fermentation; Mass transfer; Fermenter; Fed-batch culture
Concentrated nutrient solutions was fed by LAMBDA Peristaltic Pump for the production of Erythromycin from the strain Saccharopolyspora erythraea in fed-batch
Potvin, J. & Péringer, P. (1994). Ammonium regulation in Saccharopolyspora erythraea. Part II: Regulatory effects under different nutritional conditions. Biotechnol Lett 16, 69–74 (1994).
Keywords: Erythromycin; Saccharopolyspora erythraea; Antibiotic; Fermentation; Growth rate; Feeding; Fed-batch
References from Chemical laboratory, Biochemistry & DSP (Downstream processing)
Here, you will find the relevant references of LAMBDA peristaltic pumps for gradient generation and other applications in chemical laboratories, biochemistry and DSP (down stream processing):
Samples (5 mL) were extracted through a PES porous hollow fiber using the LAMBDA PRECIFLOW peristaltic pump in a suspension experiment.
Schroeder, H., Duester, L., Fabricius, A.-L., Ecker, D., Breitung,V. & Ternes, T. A. (2020) Sediment water (interface) mobility of metal(loid)s and nutrients under undisturbed conditions and during resuspension. Journal of Hazardous Materials, 19/03/2020.
Keywords: Pore water depth profiles; ICP-QQQ-MS; Peeper; Mobilization; Multi-element
The best closed reactor was selected, and the flow and contact time operation parameters were optimized for two cycles.The flow was controlled by a MULTIFLOW peristaltic pump.
García de Llasera, M.P., León Santiago, M., Loera Flores, E.J., Bernal Toris, D.N., & Covarrubias Herrera, M.R. (2018). Mini-bioreactors with immobilized microalgae for the removal of benzo(a)anthracene and benzo(a)pyrene from water. Ecological Engineering, Volume 121, 2018, Pages 89-98, ISSN 0925-8574.
Keywords: PAHBenzo(a)pyreneBenzo(a)anthraceneBioreactors; Microalgae; Alginate; Water bioremediation
MULTIFLOW peristaltic pump used to examine the influence of eluent flow rate (1.0–6.0 mL/min) in highly selective solid phase extraction
Rajabi, M., Mohammadi, B., Asghari, A., Barfi, B. & Behzad, M. (2014). Nano-alumina coated with SDS and modified with salicylaldehyde-5-sulfonate for extraction of heavy metals and their determination by anodic stripping voltammetry. Journal of Industrial and Engineering Chemistry, Volume 20, Issue 5, 2014, Pages 3737-3743, ISSN 1226-086X.
Keywords: Solid phase extraction; Nano-alumina; Sodium dodecyl sulfate (SDS); Sodium salicylaldehyde-5-sulfonate (SAS); Differential pulse anodic stripping voltammetry
The inﬂuent medium pumped using PRECIFLOW pumps to the columns containing Dehalococcoides for PCE bioremediation
Lacroix, E., Brovelli, A., Maillard, J., Rohrbach-Brandt, E., Barry, D.A. & Holliger, C. (2014). Use of silicate minerals for long-term pH control during reductive dechlorination of high tetrachloroethene concentrations in continuous flow-through columns. Science of The Total Environment, Volumes 482–483, 2014, Pages 23-35, ISSN 0048-9697.
Keywords: Organohalide respiration; Microbial reductive dechlorination; PCE; Acidification; pH buffer; Silicate minerals
MULTIFLOW pumped wastewater containing dissolved dye through the reactor with immobilized TiO2
Šíma, J. & Hasal, P. (2013). Photocatalytic Degradation of Textile Dyes in aTiO2/UV System. Chemical Engineering Transactions, 2013, 32, 79-84. Department of Chemical Engineering, Institute of Chemical Technology, Prague, Czech Republic.
www.aidic.it/cet/13/32/014.pdf (31. Mai 2021)
Keywords: TiO2 immobilization; Decolorization; Wastewater remediation; Polyacrylamide (PA); UV; Polyvinyl alcohol (PVA); Photodegradation; photoreactor
LAMBDA HiFLOW peristaltic pump with Tygon R-3603 tubing used to pump the porewater
Yuheng, W., Frutschi, M., Suvorova, E., Phrommavanh, V., Descostes, M., Osman, A. AA., Geipel, G. & Bernier-Latmani, R. (2013). Mobile uranium(IV)-bearing colloids in a mining-impacted wetland. Nat Commun 4, 2942 (2013)
Keywords: Pore water pump
Ensure column saturation with upward flow by LAMBDA MULTIFLOW pumps
Maya, C. C., Younga, L., Worsfolda, P. J., Heath, S., Bryan, N. D. & Keith-Roacha, M. J. (2012). The effect of EDTA on the groundwater transport of thorium through sand. Water Res. 2012 Oct 1;46(15):4870-82. Epub 2012 Jun 28. PMID: 22796006.
Keywords: Complexing agent; Complexation; Colloid; Migration; Modelling; Speciation
PRECIFLOW feed pump with flexible polyethylene tube for optimal growth of algae
Legendre, A. & Desmazieres, N. (2011). Device for Cultivating Algae and/or Microorganisms for Treating an Effluent and Biological Frontage. United States Patent Application 20110318819.
https://www.google.com/patents/EP2367926A2 (1. June 2021)
Keywords: Organohalide respiration; Microbial reductive dechlorination; PCE; Acidification; pH; Buffer; Silicate minerals; Bioremediation
MULTIFLOW peristaltic pump to evaluate the extraction of lead(II), chromium(III) and copper(II) on a novel adsorbent
Barfi, B., Rajabi, M., Zadeh, M.M. & al. (2015). Extraction of ultra-traces of lead, chromium and copper using ruthenium nanoparticles loaded on activated carbon and modified with N,N-bis-(α-methylsalicylidene)-2,2-dimethylpropane-1,3-diamine. Microchim Acta 182, 1187–1196 (2015).
Keywords: Ruthenium nanoparticles loaded on activated carbon; N,N-bis-(α-methylsalicylidene)-2,2-dimethylpropane-1,3-diamine; Metals; Plasma; Food; Water
Remote control of LAMBDA peristaltic pump via RS-485 interface for sample addition at 0.5 ml/hour
Scarmagnani, S., Walsh, Z., Lopez, F. B., Slater, C., Macka, M., Paull, B. & Diamond, D. (2009). Photoswitchable Stationary Phase Based on Packed Spiropyran Functionalized Silica Microbeads. e-J. Surf. Sci. Nanotech. Vol. 7 (2009) 649-652.
Keywords: Photoswitchable microspheres; Monolithic frit; Spiropyrans; Stationary phase; Metal ions
Two computer-controlled programmable LAMBDA HiFLOW peristaltic pumps for gradient generation in purification of isolated human islets
Friberg, A., Ståhle, M., Brandhorst, H., Korsgren, O. & Brandhorst, D. (2008). Human Islet Separation Utilizing a Closed Automated Purification System. Cell Transplant. 2008;17(12):1305-13.
Keywords: Human islet isolation; Islet purification; Density gradient purification; Closed system
Injection of samples using LAMBDA MULTIFLOW peristaltic pumps
Stjernlöf, A. (2007). Portable capillary electrophoresis system with LED-absorbance photometric and LED-induced fluorescence detection. Thesis for the degree in Master of Science, Analytical Chemistry, performed at Dublin City University 2007.
kau.diva-portal.org/smash/get/diva2:5248/FULLTEXT01.pdf (1. June 2021)
Keywords: Capillary electrophoresis (CE), LED‐absorbance photometric detector (LED‐AP), LED‐induced fluorescence (LED‐IF) detector, limit of detection (LOD)
Programmed MULTIFLOW feed pump to auto-regulate oxygen consumption and temperature
Vanags, J., Rychtera, M., Ferzik, S., Vishkins, M. & Viesturs, U. (2007). Oxygen and Temperature Control during the Cultivation of Microorganisms using Substrate Feeding. Engineering in Life Sciences, 2007, Volume 7, Issue 3, pages 247–252.
Keywords: Bacteria; Bioreactors; Fermentation; Process control; Substrate feeding; Temperature control; Oxygen consumption
pH-Stat: Acid and / or base pump for automatic pH regulation
pH-stat with LAMBDA PRECIFLOW acid and base pumps to maintain constant pH 4 and to estimate the biomass production
Vicente, A., Castrillo, J. I, Teixeira, J. A. & Ugalde, U. (1998). On-line estimation of biomass through pH control analysis in aerobic yeast fermentation systems. Biotechnol Bioeng. 1998 May 20; 58(4):445-50.
Keywords: On-line control; pH control; Growth monitoring; Proton titration; Yeast; Aerobic fermentation; Chemostat
pH-stat with PRECIFLOW pump for accurate quantitative determination of net proton production or consumption in chemostat cultures of Candida utilis
Castrillo, J. I., De Miguel, I. & Ugalde, U. O. (1995). Proton Production and Consumption Pathways in Yeast Metabolism. A Chemostat Culture Analysis, Yeast Vol. 11: 1353-1365 (1995)
Keywords: Yeast; N2 pathway; Chemostate; proton production; qH+; mmol h−1 per g biomass; Candida utilis; Glucose; Glycerol; Carbon source; Nitrogen assimilation pathway;
PRECIFLOW feed pump with flexible polyethylene tube
Legendre, A. & Desmazieres, N. (2011). Device for Cultivating Algae and/or Microorganisms for Treating an Effluent and Biological Frontage. United States Patent Application 20110318819.
patents.google.com/patent/EP2367926A2 (1. June 2021)
Keywords: Organohalide respiration; Microbial reducing dechlorination; PCE; Acidification; pH; Buffer, Algae cultivation
The solution was collected in a new petri dish each minute, resulting in a total of eight samples. A Lambda Preciflow peristaltic pump in combination with transparent silicon tubing (inside ⌀ = 3 mm) was used to create a flow system.
Steendam, R. R. E. & Frawley, J. P. (2019). Secondary Nucleation of Sodium Chlorate: The Role of Initial Breeding. Crystal Growth & Design 2019 19 (6), 3453-3460.
Keywords: Crystallization processes; Sodium chlorate; Water; Secondary nucleation; Chiral solid; Crystals; Fluid shear; Continuous shear-included secondary nucleation; Stationary seed chrystals; Solubility; Laser; Metastable zone; Stationary seed crystals; Seed crystal; surface
References: Laboratory pumps for food industry
Here, you will find references from scientific work in which LAMBDA laboratory pumps have been used in the food industry:
PTFE column (25 mm x 7.0 mm i.d.) and MULTIFLOW peristaltic pump: Solid phase extraction of lead, copper, and zinc from different food and water samples
Rajabi, M., Barfi, B., Asghari, A. et al. (2015). Hybrid Amine-Functionalized Titania/Silica Nanoparticles for Solid-Phase Extraction of Lead, Copper, and Zinc from Food and Water Samples: Kinetics and Equilibrium Studies. Food Anal. Methods 8, 815–824 (2015).
Keywords: Hybrid amine-functionalized titania/silica nanoparticles; Food; Water; Solid-phase extraction; Kinetic; Thermodynamic
Controlled pumping of milk into the Teflon chamber (at flow rate of 340 mL/h and 980 mL/h): Study on Staphylococcus epidermidis adherence
Jaglic, Z., Cervinkova, D., Michu, E. et al. (2011). Effect of milk temperature and flow on the adherence of Staphylococcus epidermidis to stainless steel in amounts capable of biofilm formation. Dairy Science & Technol. 91, 361–372 (2011).
Keywords: Food safety; Staphylococcus epidermidis; Hygiene; Dairy; Biofilm; Adherence